Sentence examples for robust dosing from inspiring English sources

Furthermore, this review serves to highlight the need for well-designed and conducted clinical and laboratory-based studies to provide the data from which robust dosing guidance can be developed to improve clinical outcomes in this most unwell cohort of patients.

Therapeutic drug monitoring where possible is recommended until robust dosing guidelines become available.

Well-designed clinical studies are needed to provide the data from which robust dosing guidance can be developed.

Such mechanistic and clinical PK data can then assist the development of meaningful dosing simulations and robust dosing guidelines for the prescription of antibiotic and sedative drugs given during ECMO.

This study uses meropenem plasma concentration data from four different patient populations to perform robust dosing simulations and to provide preliminary insights into the incremental effects of critical illness, ECMO and RRT on meropenem PK.

Although any drug can be affected, these findings will inform the design of future clinical PK studies [ 23] that are the next logical step in the evaluation of the impact of the circuit and drug factors on PK in critically unwell patients receiving ECMO and in the development of robust dosing guidelines.

Formed in the mid-1980s by the guitarist Bill Davis and recently inducted into the Louisiana Music Hall of Fame, the group combines fluency in American roots music with a robust dose of punk-rock spirit.

Heroin produced a robust dose-dependent locomotor stimulation in both strains.

In vivo administration in mice induced robust, dose-dependent antidepressant-like behaviors in learned helplessness models (tail suspension and forced swim tests).

We describe the use of retrogen plasmid-based vaccine technology to break tolerance and to generate a robust, dose-dependent antibody response against the self cancer antigen, survivin.

LiCl induced robust, dose-dependent taste aversions with rats receiving 0.32 mEq/kg or greater consuming a smaller percentage of the drug-paired taste than that of controls.