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We then calculated the weighted mean coverage in the remaining segments that fell within annotated CDS or RNA coordinates as gene expression value.
Hence, it is possible to label remarkably agreed predictions when two or more different algorithms coincide predicting the same target in terms of target site type and RNA coordinates.
The 23S RNA segment, nucleotides 2472 through 2650, (LSU RNA coordinates are from 1S72.pdb [ 17, 18] form the key structure of the active site, which includes the universally conserved Adenine at position 2486 adjacent to the tRNA-charged amino acid's caboxyl terminal.
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We note that the mechanisms assumed for RNA coordinated to metal ion complexes follow this mechanistic course (a noncoordinated alkoxy nucleophile with a high p Ka value), so substituting the role of the 2′OH with a carbonyl hydrate site on the ligand provides a strategy for designing complexes effective for DNA hydrolysis as well.
These small RNAs coordinate the interplay between complex signal transduction pathways.
WM cultured the cells, isolated RNA, and coordinated the project.
These results in combination reveal a functional cooperation between two RNA-binding proteins that coordinates different RNA processing steps.
HOTAIRM1 transcript is a ~500 bp RNA fragment, which coordinates along with the activation of HoxA1 and HoxA4 expression during granulocytic differentiation in NB4 cells (acute promyelocytic leukemia cell line) [ 26].
Work on the Vienna RNA Package is coordinated by ILH.
Transcription factors cooperate to mediate gene regulation; similarly, RNA processing proteins coordinate to affect gene expression.
These viral factors act in concert with host proteins to mediate virus entry and to coordinate RNA replication and virus production which is coupled to lipoprotein biogenesis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com