Sentence examples for rna breakdown from inspiring English sources

Incubation with RNAse (RNA breakdown), alkaline phosphatase (dephosphorylation), and uridine phosphorylase (breakdown of fluorouridine to 5-FU) resulted in the stepwise degradation of RNA to give 5-fluoro-uridine-3′-monophosphate (3′-FUMP), 5-FUrd, and finally 5-FU, which was analysed by GC MS (Peters et al, 1995).

The industrial production of both IMP and GMP is mainly achieved either by RNA breakdown and nucleotide extraction or by microbial fermentation using different microorganisms such as Corynebacterium, Bacillus, or Escherichia coli.

More importantly, elevated temperatures augment RNA breakdown; RNA is thermolabile and susceptible to divalent Mg2+-catalyzed degradation [18], [21], [22].

It was reported that the rate of RNA breakdown is directly proportional to Mg2+ concentration between 1 and 10 mM at above 37°C, and is increased 1.75-fold 1.75-fold 5°C increment in temperature increase above 40°C in the presence ofor mM Mg2+ [21], [22].

None of the specimens had a RIN value below six (indicating substantial RNA breakdown).

Blood samples were collected in Vacutainer PPT tubes (Becton-Dickinson) which were spun directly after collection in order to avoid RNA breakdown.

It is also shown that both cancer and RT are associated with increased oxidative damage to DNA [ 40, 41] and thus hyperuricemia might be also partly due to increased purine metabolism through the effects of xanthine oxidase as a consequence of RNA-DNA breakdown [ 42].

The positive control for KIAA1549-BRAF was RNA with known breakdown junction, which was provided by Dr Jones in Heidelberg.

Besides micro-RNA (miRNA), the new ones include small interfering RNA (siRNA), piwi-interacting RNAs (piRNA), chimeric RNA, and promoter-associated and termini- associated long and short RNAs.

One of these mechanisms involves phosphorylation, ubiquitination and proteolytic breakdown of RNA polymerase II [ 128, 129].

These unique sequences were subjected to BLAST analysis against the Rfam database to remove the ribosomal RNA, tRNA and snRNA breakdown products.