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The scale is based on survivability of brain injury, matching estimates of functional survival reported in the literature for high risk, unstable, and stable TBI.
Ideas for the model come from a literature report which describes these injuries as high risk, unstable and stable with estimates of functional survival from the trauma as 150, 350 and 600 per 1000 cases respectively [2].
The study enrols a population at particular risk (unstable coronary syndromes) and provides clinically relevant information.
In the analyses stratified by HER-2/ neu and menopausal or ER status numbers are quite small and for some risk estimates the confidence intervals are wide and the estimates of risk unstable.
II) High Risk, unstable or vulnerable plaque, with a large lipid core usually eccentric, covered by a weak and thin fibrous cap with little collagen and large quantities of macrophage and T-lymphocytes that are expression of a great inflammatory reaction that seldomly occlude the vessel significantly and is frequently not appreciated by angiography.
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When a system operates in a high-risk, unstable region, a small perturbation can induce a critical transition that leads to catastrophic failures.
However, the mechanisms by which asymptomatic fibroatheromatous plaques progress to high-risk, unstable lesions are not clear.
Patients aged ≥20 and ≤80 years discharged alive with confirmed diagnosis of ACS including ST-segment elevation myocardial infarction (STEMI), non-STEMI (NSTEMI) and high-risk unstable angina (HR-UA).
In the PROVE-IT TIMI 22 trial, 4,162 patients 10 days after an acute coronary syndrome (acute ST-segment elevation myocardial infarction [STEMI], non ST-segment elevationon ST-segmentnfarction [NSTelevationhigh-risk unstable angina) were randomyocardialtandard 40 mg pravastatinfarctionnt or high dose/aggressive 80 mg atorvastatin treatment (15).
And countries with large populations of people suffering with AIDS risk becoming unstable and susceptible to the forces of lawlessness, famine, terror and the demagogic appeals of dictators.
Although this study suggests that aspirin might differentially affect risk for unstable angina depending on CRP levels, the levels themselves weren't greatly affected by aspirin use.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com