Our obtained model of risk stratification included all the factors indicated in Table 3 and was named KemScore.
Moreover, a multimarker strategy might be also useful in refining risk stratification including mortality and morbidity prediction.
Developments in risk stratification include new classification criteria, identification of clinical risk factors, biomarkers, genetic associations, potential antibody associations and an ankylosing spondylitis-specific microbiome signature.
Limitations of this method of risk stratification include the introduction of human error into the assay protocol, resulting in inaccurate ELISA data with potentially damaging results.
Initially 155 patients were referred for risk stratification including adenosine stress SPECT myocardial perfusion imaging to assess myocardial ischaemia, andI- mIBG myocardial scintigraphy and HRV to assess CAN.
However, these parameters are often not worse than any other laboratory parameters used in risk stratification, including C-reactive protein (CRP) [ 67, 71].
26 Consensus statements on cardiac risk stratification including who should undergo screening and revascularisation and management of patients with implanted cardiac stents have been developed and widely disseminated.
There remain barriers to the routine use of risk stratification, including extensive data collection and data entry, the use of intraoperative and postoperative variables, and the inability to calculate an individual percentage mortality risk.
Prospective registries for representative regions of Europe that will include a range of variables for risk stratification including biomarkers and genetic information are warranted and will be important areas of future research.
Upon inclusion, patients will undergo non-invasive risk stratification, including beat-to-beat variability of repolarization (BVR), T-wave alternans, T-wave morphology variables, ambient arrhythmias from Holter, heart rate variability, and heart rate turbulence.
