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The development of Risk Assessment Models (RAM) for VTE risk stratification adapted for cancer patients and their prospective clinical validation is required.
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Acute lymphoblastic leukemia (ALL) is a heterogeneous disease which survival rate has greatly improved during the last decades due to improvement in risk stratification and adapted treatment strategies.
Further improvement and cost-effectiveness of the NHS breast cancer screening programme could include tomography, ultrasound and automated methods for the measurement of volumetric mammographic density (using software programs such as Quantra or Volpara) and automatically using these for risk stratification to adapt screening interval to risk.
Reported intake was converted into standard drink equivalents to enable risk stratification using questions adapted from the Alcohol Use Disorders Identification Test screening system (AUDIT-C) [ 30].
Although several molecular risk factors with prognostic and potential therapeutic implications have been identified, such as mutations (NOTCH1) or aberrant expression (BAALC, ERG, TLX1, TLX3), there is still a need for more precise molecular risk stratifications to guide adapted treatment strategies.
These findings provide an opportunity to adapt risk stratification and treatment schedules and to identify new druggable targets.
Machine learning paradigm is adapted for risk stratification of psoriasis disease grades utilizing offline training and online testing images.
The Medical Research Council (MRC) UK ALL 2003 (UKALL 2003) randomized control trial (registration number ISRCTN07355119) tested whether MRD-based risk stratification allows the intensity of therapy to be adapted to the risk of relapse.
Verlohren and coworkers proposed that sFlt-1/PlGF ratio may be used in individualized risk stratification in patients with clinical preeclampsia, and clinical management can be adapted accordingly [ 17].
Furthermore, samples from the Cytosponge have the potential to be adapted for surveillance, with the application of suitable risk stratification biomarkers.
Intravascular ultrasound (IVUS) is most commonly adapted for screening, but current tools lack the ability for risk stratification based on grayscale plaque morphology.
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