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They report 13 new regions associated with celiac disease risk, identify multiple independent signals at several loci and refine the localization of many previously reported risk signals.
For investors who live in the long term, though, risk levels and risk signals are much more so.
Other economic risk signals include rising interest rates, which we don't see at the long end of the curve, where it really matters; and rising oil prices, which are not yet in the danger zone.
Nevertheless, these risk signals were ignored, despite the relatively simple approaches to mitigate and respond to their presence.
Most risk loci seem to be shared, whereas the risk signals often appeared to be population specific.
Three of these risk signals are represented by SNPs in localized clusters of moderate LD, whereas the fourth appears to be more tightly defined.
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I should be grateful if you would advise me as a matter of urgency what action you intend to take to mitigate against this high risk signal".
As the financial gatekeepers of a company, CFOs and investor relations officers need to address climate change and sustainability issues or risk signaling to the board and investors that management does not see the strategic importance of those matters or grasp their financial impact.
In this context, should we risk signaling that female-headed single-parent families, undeniably economically needy as they may be, should have their housing needs accommodated, lest they be counted among the "family homeless"?
At the same time, by providing for these "homeless" (that is, those who lack their own home, even if they're not living on the street), we risk signaling the establishment of a social norm: that single-parenting is a fact of life that we, through government, will seek to accommodate and make more comfortable.
That's putting the Andean staple at grave risk, signaling the potential for famine and the unraveling of folkloric customs in indigenous communities scattered amongst the region's snowcapped peaks and valleys.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com