Sentence examples for risk reduction estimates from inspiring English sources

(7) Rebbeck, T, et al. Meta-analysis of Risk Reduction Estimates Associated With Risk-Reducing Salpingo-oophorectomy in BRCA1 or BRCA2 Mutation Carriers.

16 We used random effects models to summarise relative risk and absolute risk reduction estimates.

Another explanation might be the difference in the definition of outcomes and the relative risk reduction estimates used in each study.

For each trial we retrieved or calculated the crude relative risk and absolute risk reduction estimates and corresponding 95% confidence intervals for the assessed outcomes.

25 To estimate a pooled time to benefit, we combined survival data from all four studies to obtain pooled annual risk reduction estimates, allowing the time to specific absolute risk reduction thresholds to be determined.

This implies that our risk reduction estimates of hospitalizations for RSV-related bronchiolitis should range between 53% and 67%, very similar to those previously reported in the two clinical trials.

Strategies for validating biomarkers and minimizing the degree of bias in the risk reduction estimate are discussed.

We then multiplied the extreme values of this range by the common risk reduction estimate.

Using data from the 10-year DPP risk reduction estimate (SA5) resulted in higher ICERs, as did assuming a long-term diminishing effect of the intervention (SA6).

Table 3 shows these parameters in a cluster analysis, the effect size (absolute difference and relative risk reduction estimated as 1−relative risk), precision (95% confidence interval), P value and degrees of freedom, and intraclass correlation coefficient.

Such differences in study design can introduce biases (such as survival bias), and can consequently have an impact on risk-reduction estimates.