"At the same time it can deliver a commercially risk-adjusted return for investors on a significant portfolio of London property without the risk of voids.
Women not willing to undergo a procedure due to risk of voiding difficulties.
6 Lee et al reported benefits for men with OAB symptoms from an initial combination treatment of an alpha-blocker with anticholinergics, without increased risk of voiding difficulty and acute urinary retention.
This technique allows the operator to achieve a thin layer of sealer despite irregularities in the canal wall, hence minimize the risk of voids between canal wall and filling.
Based on the time frame of the study and the number of women currently seen in our CISC clinics and having treatments which have a risk of voiding difficulties attached to them, we expect to recruit 130 women.
This figure is based on the number of women who attended a nurse-led clinic to learn CISC over the previous 12 months and treatments that have a risk of voiding difficulties attached to them.
For the qualitative aspect of this project, we will aim to recruit a purposive sample which will include five women from each of the following four groups, a maximum of 20 women in total: Women not willing to undergo a procedure due to risk of voiding difficulties.
Although a large proportion of cases will not progress to a life-threatening state, a diagnosis of PCa can have significant daunting effects on the patient and his family, with concomitant lifestyle changes, particularly due to the high risk of voiding and sexual dysfunction resulting from currently available curative treatment options.
Participants will include women who have pre-existing voiding difficulties or, are at risk of developing voiding difficulties due to this pathology and/or the proposed treatment.
One of the reasons for this could be that the canal anatomy impedes adequate cleaning of the narrow fissured areas with circular root files since the canal lumen is irregular and the risk of subsequently creating voids is high [ 11,12].
