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Microcirculatory flow abnormalities at the baseline were independently associated with an increased risk of unfavourable outcome.
The highest risk of unfavourable hygro-thermal conditions is usually presented in location characterized by thermal bridge, such as foundation, window-wall, wall-roof and wall-floor junctions.
Plasma should not be used to correct abnormal INR or PTT in nonbleeding patients who have no planned surgery or invasive procedures, because there is no correlation between coagulation tests and risk of bleeding [45], but data show that plasma transfusions increase the risk of unfavourable outcome [27, 28].
Coinfection with HCV/HBV viruses usually is associated with higher risk of unfavourable course, treatment difficulties and rapid progression of liver fibrosis.
In order to control for acute injury severity, an acute injury composite was calculated representing risk of unfavourable outcome at 6 months.
In the management of depression, these deficits lead to frequent interruption or premature termination of drug therapy, which increases the risk of unfavourable depression outcomes [ 8, 9].
Similar(45)
Although both models tended to over-predict the risks of long-term unfavourable outcome, the IMPACT model had a slightly better calibration than the CRASH model (intercept of the calibration curve = −4.1 vs. -5.7, respectively), especially when the predicted risks of unfavourable outcome were < 80%%.
In general, protocols for empirical antimicrobial treatment are based on information about the most likely pathogens involved, prevalence of resistance in these pathogens and risks of unfavourable outcome when therapy is not appropriate.
Additionally, long term storage (e.g. more than 4 weeks) at clinics should be prevented as this potentially could lead to loss of samples or increase risks of unfavourable storage conditions that could lead to degradation of antibodies or antigen [ 12].
Headache onset early in life increases the risk of an unfavourable clinical course and also genetic factors play an important role in the phenotypic expression of the disease.
In a recent placebo-controlled trial for adjunctive dexamethasone therapy in adults with bacterial meningitis, treatment with dexamethasone was associated with a reduction in the risk of an unfavourable outcome (relative risk, 0.6; 95% CI, 0.3 0.9; P = 0.03) and mortality (relative risk of death, 0.48; 95% CI, 0.2 0.96; P = 0.04) [29].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com