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Yet, the language of dehumanisation and destruction is alarmingly reminiscent of the very darkest chapters in our world history; to avoid the risk of replication, we must maintain the distinction between offender and offence — whatever the circumstances.
Rapid progression through successive rounds of DNA replication and mitotic division may expose ES cells to increased risk of replication errors, which are the most common source of double strand breaks (DSB) in proliferating cells.
If integrated into bacterial genomes, such damaged DNA may further produce new genetic variation during genome replication because of the increased "risk" of replication errors.
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Mathematical analysis has shown that given a maximal allowable fork density, an increasing I t) minimizes the risk of incomplete replication by allowing fork proteins to be efficiently reused [15], [16].
The risk of unnecessary replication of diagnostic tests, of adverse drug-drug or disease-drug interactions and of treatment errors rises in individuals with multiple chronic conditions [ 33].
This difference persisted up to month 6 suggesting that corticosteroid exposure was an important modulator of the risk of BKV replication early posttransplant.
This exposure results in elevated mitotic proliferation of endometrial cells which, in turn, increases the risk of DNA replication errors and DNA mutations which can lead to endometrial cancer [ 2].
A similar observation was made in hematopoietic stem cell transplant recipients where a trend for reduced risk of CMV replication and lower CMV viral loads was observed in a minor allele background.
Although there are lingering biosafety concerns regarding HIV-1 based lentiviral vectors, the current third-generation replication-defective and self-inactivating (SIN) lentiviral vectors have minimized the potential risk of generating replication-competent helper virus[ 31].
The GV11 adenoviral backbone was chosen to reduce the risk of generating replication-competent adenovirus during clinical production.
This view arose from the theory that biological systems ought to protect stem cells from the risks of DNA replication and led to the notion of quiescence as an inherent property of the stem cell fate.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com