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Roughly speaking, this additional step of calculating controls' residuals based on individualized control models reduced the risk of fitting model parameters too closely to the control data, thereby modeling the idiosyncrasies of each individuals' performance and underestimating the variability in control performance.
Professionals stated the risk of undetected pathology, the risk of wrongful indications for a hearing aid, and the risk of fitting hearing aids for commercial reasons only.
Fitting models to these expression profiles would therefore greatly increase the risk of fitting equations that have no causal relationship with transcript accumulation.
Higher order functions like a triple sigmoid would probably improve the goodness of fit, but also increases the risk of fitting artefacts.
They are also highly dependent on the quality of the data, and since they have the flexibility to adjust to small nuances in the data there is a risk of fitting to noise.
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So what, are we trying to tell you to not wear something at the risk of not fitting in?
We did not select features because the number of motifs in our dataset was very large which made it possible to include many features with a low risk of over fitting.
Instead of taking risks with the objective of fitting in, take a risk by being brave enough to reach beyond your wildest imagination and see yourself as a girl that has everything necessary and know that you, as you are, is enough.
The quality of these datasets combined with the large number of parameters used in their fitting induces us to suppose a risk of over-fitting.
The results of fitting a continuous risk function to reflect the patterns of risk of specific outcomes across regions containing an incinerator need to be interpreted carefully.
Cross-validation was used to reduce the risk of over-fitting the data during the assessment of the model.
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CEO of Professional Science Editing for Scientists @ prosciediting.com