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"Whenever you measure a large number of outcomes you increase the risk of chance findings," he said.
In contrast, a large number of statistical tests have been performed in this study which increases the risk of chance findings.
Firstly, the number of subjects was rather small increasing the risk of chance finding.
We tested multiple associations between exposures and outcomes with inherent risk of chance findings.
The large sample size decreased the risk of chance findings and facilitated extensive subgroup analyses.
There is of course a risk of chance findings when performing multiple tests, as in this study.
Similar(33)
Permutation experiments indicated a low risk of chance-correlations (see File S1).
Permutation experiments again indicated a low risk of chance-correlations (see File S1).
Moreover, multiple subgroup analyses increased the risk of spurious chance findings.
Through bootstrapping we have tried to lower the risk of reporting chance findings.
Finally, identifying patient characteristics that predict questionnaire response and health utility involved multiple hypothesis testing with the associated risk of spurious chance findings.
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