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Future work to understand infection processes in more detail for these microbes is necessary, not only for the sake of general knowledge, but also because the diversity of plausible dose-response functions for each microbe may yield different estimates of infection risk, and different risk management conclusions.
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Development of 3D city models (3DCM) in this study, as support for urban risk management, follows the conclusion drawn by several authors (Kemec et al. 2009, 2010; Zlatanova 2008): 3D graphical representations embody a means of communication that is even more effective than the 2D maps already commonly used in studies of vulnerability, hazard, and risk.
According to our results, the conclusion of the EFSA GMO Panel [1, 4] "that the previous GMO Panel risk assessment conclusions and risk management recommendations on maize MON810, Bt11 and 1507 for cultivation remain valid and applicable" is, therefore, not scientifically justified.
Since within and close to the Bt-maize field the estimates of mortality made by the GMO Panel [9 13] exceed those that would be derived assuming the Hofmann et al. [2] relationship, there was no need to revise the consequences for the previous EFSA risk assessment conclusions and risk management recommendations for Bt-maize for NT larvae within the field and its margins".
Furthermore, criticisms of EFSA EFSAA J 2015(13):4120152015) and of EFSA [Relevance of a new scientific publication (Hofmann et al. 2016) for previous environmental risk assessment conclusions and risk management recommendations on the cultivation of Bt-maize events MON810, Bt11 and 1507.
We reiterate the severe methodological criticisms made by EFSA [Relevance of a new scientific publication (Hofmann et al. 2016) for previous environmental risk assessment conclusions and risk management recommendations on the cultivation of Bt-maize events MON810, Bt11 and 1507. EFSA Supp Publ; EN-1070, 2016], which render this estimation procedure unreliable.
The EFSA Panel [1] reacted to the findings of Hofmann et al. [3] by ignoring the relevance of these empirically based results and stated that "EFSA considers that the previous risk assessment conclusions and risk management recommendations on maize MON810, Bt11 and 1507 for cultivation made by the Panel on Genetically Modified Organisms remain valid and applicable".
Instead of focusing on a purely formal adherence to high quality claims, the member states should primarily examine - based on the submitted information - whether the conclusions drawn in risk management are sufficient and acceptable.
Conclusions are drawn in terms of risk management of agricultural water recycling as an integrative process for managing associated land use needs.
Instead, conclusions on risk assessment and risk management should be updated based on the model described here for the distance relationship of maize pollen deposition under common cultivation.
Subsequent conclusions on the necessity of further risk management measures are still pending for most substances.
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