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Quantifying risk is further complicated by the absence of data regarding the factors affecting disease transmission.
This risk is further complicated by the intrinsic variability associated with lineage-specific differentiation of hESCs or hiPSCs.
When the pharmacokinetic profile is not known in a first-in-human dose trial, the assessment of QTc risk is further complicated by the overall condition of the study population, consisting of terminally ill patients with heavily pretreated conditions receiving several comedications and suffering from coexisting disease.
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Moreover, the use of such information for risk assessment is further complicated by the association of the rapid phenotype with increased risk in colon cancer and the slow phenotype with increased risk in urinary bladder cancer.
Risk analysis is further complicated by the uncertainty in aquifer properties and contaminant conditions.
Sanitation, on the other hand, has little relevance on a risk framework and is further complicated by a highly fragmented market and an investment climate that doesn't offer much for ease of entry.
The risk of co-migration is further complicated by the fact that sequences of different lengths may migrate together for a variety of reasons, including physical damage to the DNA molecule, differences in base pair composition and/or methylation [ 9].
Managing risk factors such as disturbance is further complicated by the fact that they require a landscape scale perspective, and the cooperation of actors at large scales depends on people's beliefs and norms about reciprocity, as well as on the (perceived) benefits of interacting with others (Fischer and Charnley 2012).
With such low relative risk, replication of true positive findings is further complicated by chance findings, as well as differences in ascertainment.
And the situation is further complicated by the risk of social and political unrest, in a country where a food crisis that led to violent riots in April remains unresolved.
Estimating the risk of PCP during induction of remission is further complicated as therapeutic strategies have changed over time, leading to lower cumulative Cyc doses and less frequent use of high dose intravenous GCs.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com