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Though these studies present a low replication, more evidence supports that the etiology of schizophrenia involves, rather than single genes/loci with large effect, many genes, each of which contributes a small risk, interacting with each other or with environmental risk factors to cause schizophrenia [3].
It also said the closure of the Independent Living Fund and changes to housing benefit "risk interacting in a particularly harmful way for disabled people".
To the extent that the intrauterine environment is in fact more similar for DZ twins than for nontwin siblings, it is also possible that the increased recurrence risk of DZ twins compared to nontwin siblings reflects a shared genetic risk interacting with shared prenatal exposures [ 46, 47].
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We find that genetic risk interacts with LBW for gestation in influencing depression.
Here we present a biologically plausible model in which the two variables affecting risk interacted neither multiplicatively nor independently.
Emerging and reemerging disease risk interacts with socioeconomic vulnerability to determine the populations at highest risk for infection and those most likely to import pathogens into the country.
Standard regression analysis treating birth-weight for gestation as a continuous variable also showed that familial risk but not genetic risk interacts with birth-weight.
Hence, the effect of COPD on suicide risk interacted significantly with psychiatric history (test of effect difference: χ=47.55, p<0.001 after adjustment for sociodemographic variables).
Methylated paired box 5 protein transcription factor (PAX-5a), although not being associated with asthma risk, interacted synergistically with PCDH-20.
Polygenic risk interacted with cognitive ability (p =.02), predicting HbA1c levels more strongly in people with below-median cognitive ability (effect r =.21) than in people with above-median cognitive ability (effect r =.10).
Increasing numbers of external risks interacting with economic and social problems may lead to 'a wider set of scenarios for welfare futures than we have seen in the past' [68, 70].
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CEO of Professional Science Editing for Scientists @ prosciediting.com