Sentence examples for risk inheritance from inspiring English sources

We considered these 14 SNPs in a recessive risk inheritance model, corrected for local and global ancestry, and applied a false discovery rate (FDR) multiple comparison correction to their P-values (17).

Nevertheless, this analysis successfully and importantly replicates a positive association of these previously reported MYH9 polymorphisms with non-diabetic ESKD under a recessive risk inheritance model in a new population sample, with a different African European ancestry admixture proportion.

To examine the excess information in pairs of SNPs, we chose one representative SNP from each of the sets E-1 (rs4821481), S-1 (rs5750250), F-1 (rs11912763), and for each such pair, modeled association using both SNPs according to the risk inheritance mode which yielded the most significant association (recessive for E-1 and S-1, dominant for F-1).

Table  3 summarizes the association results based on the primary analysis for these 10 SNPs, which yielded any P-values of <0.05 with any combination of risk inheritance model (recessive, dominant or additive) in the non-diabetic groups (African Americans, Hispanic Americans).

Genetic testing confirmed a CCM2 mutation heterozygous deletion of two-nucleotides and 50% risk of inheritance of the c76_77del to family members.

Moreover the skeletal and facial features demonstrated different risk of inheritance according to the gender.

Quantitative studies have observed that, for example, patients with familial hypercholesterolaemia (FH) have a poor understanding of risk and inheritance [ 25].

However, while in monogenic conditions the genetic counselling is usually sufficient to quantify the risk of inheritance of the specific disease, in a polygenic scenario this is not the case.

"The trick is to strike the right balance between giving them enough so they'll take it and not contest it and risk losing their inheritance," Ms. Klein said.

The study group goes with him for moral support and must all pitch in to play the video game of their life on Pierce's behalf - or risk losing his inheritance.

Another component of T1D that aids in our understanding of the disease and assessment of risk is genetic inheritance.