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(4 where Pr k is the probability of occurrence for the k-th state, Risk k (Pr k, x k ) is the corresponding risk computed by given probability Pr k and state x k, Riskmax is the limit of the system security level.
†Excess risk computed as absolute difference in remaining lifetime risk between men and women.
Data are from Table 5 of [5] with number at risk computed by dividing number of breast cancers by reported breast cancer rate.
We applied our approach to 13 experienced readers assessing 13,694 screening mammograms from a large clinical study where women are categorised as high risk if they have a 5 to 8%10-year10-yearcomputed by a validated risk model and their breast density is in the top decile of the study population.
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Consequently, the incidence risks computed here are expected to be under-estimates of the true risk in the population.
Without appropriate adjustment, however, derived genotypic risks computed are inflated, hence the upper confidence limits of the risk of CRC associated with the variants in our study will be overoptimistic.
We compared the cumulative incidence of cervical intraepithelial neoplasia grade II or worse for immediate large loop excision versus biopsy and selective recall using relative risks, computed by Poisson regression.
Numbers of patients at risk (n risk ) were computed at time point 0, 5 and 10 year, respectively.
Cardiovascular risks and breast cancer risk are computed thanks to published risk prediction models [ 7, 8].
In these models, the relative risk was computed as the risk of preeclampsia in a specific quintile of intake compared to the risk in the lowest quintile.
These risk scores were used to categorize patients into low-risk or high-risk groups, dichotomized using the median risk score computed on the training dataset.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com