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Secondly, the risk coefficient for heritable disease is considerably lower than previously assessed.
For the computation of the total detriment adjusted risk, the risk coefficient for cancer (5.5 × 10-2 Sv-1 for the whole population [32]) with an age-dependent correction for the higher cancer risk for children [37] is needed as well.
We could improve the models for use in our setting by recalculating the risk coefficient for the chosen variables.
Across all BSC plants, the relative risk coefficient for working 5 or more years on ovens tops, where the exposures were highest, was 1.81, which was statistically significant.
The corresponding risk coefficient for irradiation in the third trimester for childhood cancer deaths at ages 0-15 years = 4-5 x 10 -4) per cGy fetal whole body dose (95% CI 0.8-9.5 0.8-9.5) per cGy).
The change in the outcome (Δ y) associated with a change in exposure (Δ c) is a function of the baseline incidence rate (y) and the risk coefficient for a one-unit increase in exposure: where β = [ln RR)]/ c.
Similar(51)
Risk coefficients for PM10 and ozone at various time lags after the exposure are reported in the eAppendix (http://links.lww.com/EDE/A778).lww.com/EDE/A778
Joining Dr. Muihead's conclusion, these results thus suggest that the most relevant risk coefficients for radiation protection concerns are estimates excluding patients with PFs.
> Re-estimating the risk coefficients for the estimated hidden data, we find a somewhat stronger overall effect (P=0.10; likelihood ratio test).
It will be seen from this table that none of the risk coefficients for young children is statistically significantly different from zero.
In particular, the risk coefficients for age, sex and the incremental risk for each of the stages were forced to be non-negative (i.e., the overall risk was imposed to increase with age and stage and to be higher in men than in women).
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