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This magnitude of clonogen density would correspond to a high risk (aggressive) type of tumour [ 24, 25].
In patients with a higher mortality risk, aggressive intervention, including admission to the intensive care unit, should be considered.
An ameloblastoma is a benign odontogenic tumour that exhibits a high recurrence risk, aggressive behaviour and local invasiveness [ 1].
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Standard-of-care treatment for high-risk (aggressive) neuroblastoma includes induction therapy (initial treatment) with multidrug chemotherapy and surgery.
While the pediatric antidepressant debate has focused on potential suicide risks, aggressive behavior can be a side effect of antidepressants.
The Coping Power program is an indicated prevention program for at-risk aggressive preadolescent children, and has had demonstrated short-term effects on antisocial outcomes.
Chao, NJ, Rosenberg, SA, and Horning, SJ. "CEPP(B): an effective and well-tolerated regimen in poor-risk, aggressive non-Hodgkin's lymphoma". Blood 76, no.
It could just be that if McLaren relaxed a little, didn't stake all on high-risk aggressive strategy, they might just be able to take the fight to Red Bull regardless.
These alterations could define the switch from favorable NB to high-risk aggressive disease.
These MSDACs also initiated and reproduced high-risk aggressive metastatic disease in vivo.
In conclusion, the results of this study show an accumulation of genetic rearrangements in neuroblastoma cells that drive high-risk aggressive metastatic disease.
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