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We retrospectively enrolled all patients admitted to a mixed medical-surgical trauma ICU from January 2007 to August 2008 who showed a >72 hours length of stay and were >18 years old; exclusion criteria were DVT at admission and/or within the previous 6 months, thrombophilic profile, high haemorrhagic risk, admission from another ICU.
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The calibration plots indicate that APACHE III significantly underestimated mortality for all admissions, whereas APACHE II appears to overestimate mortality for higher risk admissions.
Patients with 'high-risk' admission diagnoses should be monitored carefully for signs of feed intolerance during enteral feeding so that treatment for feed intolerance can be instituted early to prevent reflux complications and optimise nutritional support.
Social risk factors such as homelessness and mental illness have also been proposed as reasons for low-risk admissions [ 23– 25].
Among these high-risk admissions are old and multi morbid patients, patients with chronic diseases, open wounds, eczema, burns, and patients requiring dialysis.
Should a universal screening of all inpatients be conducted or a targeted screening program limited to high-risk admissions or areas of the hospital?
The logistic model for risk of admission compared community controls with all admissions.
"Admission on Saturday was associated with a marked increased mortality (death) risk and admission on Monday was associated with a less, but statistically significant, increased risk".
Living with a child reduced the risk of admission to a home for the elderly but increased the risk of admission to a nursing home.
140 141 The baseline risk of admission was 41%; after recruitment of the initial 320 patients, the observed overall risk of admission was substantially lower at 16%, which substantially reduced the effective sample size from 1200 to 800.
The risk of admission for heart failure increased for seven traditional NSAIDs (diclofenac, ibuprofen, indomethacin, ketorolac, naproxen, nimesulide, and piroxicam) and two COX 2 inhibitors (etoricoxib and rofecoxib).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com