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Indeed, we note that transcriptional pausing and arrest may largely be stochastic, and that it does not necessarily increase with rising gene expression levels, potentially helping to explain why the occurrence of CFSs, although typically occurring in genes, is not correlated with their transcription level (Le Tallec et al., 2013).
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Taken together, these analyses demonstrate that this rose gene expression atlas is a reliable source for candidate genes associated with male reproductive processes.
With the exception of the sex chromosomes, the genome is essentially identical between the males and females of an inbred mice strain, hence the possible mechanisms that give rise to gene expression and/or splicing variation include trans-acting factors on the sex chromosomes (such as SRY or the Sox proteins), epigenetic variations, and/or hormonal differences.
When using RT-PCR ELISA, the initial rise was again seen followed by a return to baseline values at the time of rejection diagnosis followed by a further significant rise in gene expression after the start of anti-rejection treatment.
A Dex-on, Tet-off system has been described in plants [27], but in that case the administration of the inducer and the antagonist are simultaneous, and do not give rise to gene expression "waves" like the ones described here.
For the six other patients no rise in gene expression level could be found.
In the recent years, there has been a rise in gene expression profiling reports.
Fracture resulted in a rise in gene expression in both age groups to a peak at two weeks after fracture.
Fracture resulted in a rise in gene expression for both age groups to a peak at one to two weeks after fracture.
This major trend is a rise in gene expression during late pregnancy that remains high during lactation and falls during involution.
These findings indicate that Smad1, 5, and 8 upregulation is an early and specific event in the muscle of ALS mice, and that the gradual rise in gene expression, particularly Smad8, parallels disease progression.
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