Sentence examples for ring substrates from inspiring English sources

RING substrates (RING) or HECT and other substrates (HECT) are submitted to the DAVID website with the background of the whole human proteome.

SmelDhp presents both hydantoinase and dihydropyrimidinase activities, with higher affinity for the natural six-membered ring substrates.

For the five-membered ring substrates, affinity was greater for those with aliphatic and apolar groups in the 5th carbon atom, with the highest rates of hydrolysis for d-5-methyl and d-5-ethyl hydantoin (kcat/Km = 2736 ± 380 and 944 ± 52 M−1 s−1, respectively).

The S. meliloti CECT4114 dihydropyrimidinase is described to hydrolyze substituted five-membered and also six-membered ring substrates (Martinez-Rodriguez et al. 2010b).

The second component can be thought of as representing discrimination between fused ring substrates (PROP, 2A5C, and MDOB) and phenolic ether substrates (12-pNCA, 11PA, 2PE).

However, another major component of the relationship is the tendency of the P450 to favor either the phenolic ether or fused ring substrates.

In addition, four 9310 steel substrates fixed uniformly along the circumferential direction of a metal ring substrate were irradiated by this annular cathode HCPEB source.

The most likely scenario is that LUT1 has a higher affinity towards ε-rings vs. β-rings and that, when α-carotene is available, LUT1 performs mainly ε-ring hydroxylation; however, since no ε-ring-substrates are available in the chy1chy2lut2lut5, the β-ring substrates are processed, thus bringing out this minor activity of the enzyme.

Simian immunodeficiency virus (SIV) and HIV accessory proteins exploit these characteristics by modifying the specificity of Cullin-RING substrate receptors (e.g., HIV-1 Vif and Vpu redirect cullin-1 and cullin-5 receptor specificity to induce APOBEC3 and Tetherin restriction factor downregulation, respectively) (Guo et al., 2014; Mitchell et al., 2009).

The catalytic activity of PTPN18 towards the three phosphorylated peptides of HER2 was five orders of magnitude higher than towards the single phenyl-ring substrate, suggesting that the residues flanking the HER2 phosphorylation sites are among the determinants of the recognition of these sites by PTPN18.

Thus, CAND1 mutant plants show distinct phenotypes and accumulation of cullin RING ligase substrates.