Exact(2)
The secosteroids, comprising various forms of vitamin D, are characterized by cleavage of the B ring of the core structure.
The fibrillar structure on the nuclear side, called the basket, consists of eight fibrils attached to the nuclear ring of the core.
Similar(58)
In both sub-libraries substitutions were carried out with six different groups resulting in six pairs of compounds differing in only the heteroatom of aromatic ring of the cores.
We estimated dates for cores without pith by overlaying sets of concentric circles on the inner rings of the core [47].
The outer rings of the core act as gates to the core and each is composed of seven α-subunits.
We estimated dates for cores without pith by overlaying sets of concentric circles on the inner rings of the core [ 47].
Proteolytic degradation of the target protein takes place within the rings of the core subunit following removal of the ubiquitin monomers by deubiquitination enzymes (DUBs) and unfolding of the substrate protein [ 44].
The two most evident structurally relevant cross-ring cleavage ions resulting from the ring split of the core branching β-Man abundantly detected at m/ z 709.32 (Man3-O-CH2-CHO; A-type ion) and 737.35 (Man3–O–CH2–CH=CH–O–CH3; A-type ion) are diagnostic ions of the presence of a fully methylated trimannose unit linked to the Manα1,6 arm.
Optimization of the benzamide and central ring components of the core scaffold led to the identification of a GlyT-1 inhibitor that demonstrated in vivo activity in a rodent cerebral spinal fluid (CSF) glycine model.
In order to study the influence of different imidazole derivatives in triphenylamine-based organic dyes, two different imidazole derivatives are introduced into the phenyl ring of the triphenylamine core, coded as CD-4 and CD-6, respectively.
By the evaluation of the studies related to the structure activity relationships on QD and its derivatives, the clear evidence was observed that the antimicrobial activity has been associated with the structural diversity at the benzyl chain or/and at the quinoline ring of the QD core.
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