Several chemical modifications have been performed on positions C-3 and 8 of the naphthalene ring determined as primary targets for the agomelatine metabolism.
The observation of interference effects in both systems indicates that the coupling to the central benzene ring determines the occurrence of quantum interference effects, while the spacers and anchoring groups slightly tune the conductance through the molecular junction.
The obtained models additionally represented how the electronic and steric effects of substituents attached to the hydantoin ring determine biological partitioning and interactions of the compounds with target sites.
The orientation of the line, in combination with the location of the currently fixated ring, determined the next saccade target.
The substituted group and its location on the polyphenolic ring determine the type of anthocyanidin and may also dictate aspects of biological activity.
Six rings determine the scoring: an inner bull's-eye worth 50 points, an outer bull's-eye worth 25 points, a wide single-scoring ring, a narrow triple-scoring ring, another wide single-scoring ring, and, outermost, a narrow double-scoring ring.
These cooperative hydrogen-bonding forces and various π-forces (π⋯π, Cu II)⋯π, carbonyl⋯π) involving 1,10-phenanthroline aromatic rings determine the overall packing of the molecular units in the unit cell.
This ring will determine the tree size--the bigger the ring, the larger the tree.
Scientists ushered in the development of multigrade motor oils by bombarding piston rings with neutrons, determining the rings' wear and other characteristics.
θ exo = A θ endo + B. As the set of all five endocyclic torsion angles in a five-membered ring fully determines its conformation, 3J HH scalar coupling constants provide a direct measure of the ring's conformation.
Relative abundance of GFP and mCherry (total numbers) per ring was varied systematically as above, and the number of FRET pairs per Tub4 ring was determined in each experiment.
