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With an incidence of 7.8 confirmed events per 10 000 exposure years, the vaginal ring conferred a 90% higher risk of venous thrombosis than did combined oral contraceptives containing levonorgestrel, bringing the risk to the same level as that of combined oral contraceptives with third and fourth generation progestogens, and compatible with the Food and Drug Administration study.
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6 8 20 Use of transdermal patches and vaginal rings conferred incidence rates of 9.7 and 7.8 confirmed venous thromboses per 10 000 exposure years, and relative risks of 7.9 and 6.5 compared with non-use of hormonal contraception, respectively.
Both five- and six-member ring structures conferred similar activity, and this activity was generally retained despite a variety of substitutions within the ring and/or the presence of additional methyl groups at different positions around the ring.
Introduction of an aliphatic amine chain on the N atom of the phenothiazine B ring (promazine) conferred inhibitory activity toward NOX2, NOX4, and NOX5 but not NOX1 and NOX3.
BCA2's RING domain confers autoubiquitination activity, consistent with other E3 ubiquitin ligases such as RING proteins MDM2 and SIAH1 [ 2, 9, 10].
With the help of the ring, which confers invisibility, Bilbo escapes and rejoins the dwarves, improving his reputation with them.
In addition, a C-terminal really interesting new gene (RING) domain confers API2 with an E3 ubiquitin ligase activity [9], and ubiquitination-induced degradation of pro-apoptotic proteins like SMAC/DIABLO [10] might contribute significantly to its anti-apoptotic function.
In addition, incorporating the reactive centre within a heterocyclic ring system confers inducer activity (compare K-6 with K-1).
The BDFIG retains the benefits of the DFIG, i.e. variable speed operation with a partially rated converter, but without the use of brush gear and slip rings, thereby conferring enhanced reliability.
The Roman Catholic church conferred episcopal rings upon newly appointed bishops, and so-called papal rings were given by popes to cardinals.
A principal contact between the isoquinoline or adenine ring with APH is the stacking interactions conferred by the aromatic ring side chain of Tyr42 in APH(3' -IIIa and Phe50 in APH(9)-Ia (Figure 2).
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CEO of Professional Science Editing for Scientists @ prosciediting.com