Sentence examples for ring alteration from inspiring English sources
In contrast to modifications on the oxazine ring, alteration of the ester substituent at C2 resulted in a pronounced increase in biofilm inhibition.
Out-of-ring altercations, commonplace in boxing, never fail to blur the lines between reality and preconceived theatrics designed to promote a fight.
However, the 4′-position of the C-ring was tolerant to alteration and does not show significant loss of activity after replacement with different functional groups.
We focused our investigation on small changes in the pyrimido ring of M1dG that imparted alterations to size and conjugation as well as the addition of substituents.
Similarly the fourth ring illustrates the copy number alterations in hiPSC samples [ 42] and lastly the associated genes with them in the same samples (unpublished observations, Laurila et al. submitted).
Biological evaluation revealed that alterations to the aromatic ring had a significant effect on affinity for gp120 and the degree of CD4 mimicry.
These effects may result from direct modification of TJ proteins such as occludin, claudin, and ZO-1, or by alteration of the perijunctional actomyosin ring [1], [2], [3].
Subsequent SAR work has been reported using 6,6,8-triethyldesmosdumotin (TEDB) as the lead with structural alterations of the B phenyl ring.
Alterations of the 20-membered disulfide ring either by amino acid deletion or by substitution resulted in impaired catalytic activity.
