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The main question is whether the data are sufficiently diverse and rigorous to answer the research question [ 43– 43].
In order to produce new knowledge, research has to be designed and conducted in ways that will produce reliable results; in particular, it must contain a significant and clearly articulated study question, and its design must be sufficiently rigorous to answer that question.
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Epidemiologists look for patterns of illness in populations, and Dr. Winkelstein was considered a master at designing rigorous studies to answer tough questions about the causes, risk factors and transmission of disease.
Thus, based on the findings from BLING I, BLING II was designed with rigorous and stringent methods to answer the ultimate question of whether administration of beta-lactam antibiotics by CI will result in improved outcomes for patients with severe sepsis.
Methodologically rigorous research designed to answer these questions would be useful for treatment decisions.
Little rigorous evidence exists to answer risk compensation concerns in the biomedical HIV prevention literature, in part because the field has not systematically evaluated the study designs available for testing these behaviors.
And his influence on the state media -- his own and allied parties partly administer the state networks, which run on a partisan spoils system -- has meant that he has never been forced to answer rigorous questioning on the investigations.
The ISQ is based on common scientific criteria in all research based on rigorous methods that aims to answer questions of effect.
As with those who work on education, poverty alleviation, and other social-sector programs in developing countries (who frequently rely on evidence from randomized evaluations),, global public health practitioners should use the most rigorous, systematic approaches available to answer questions and make decisions in the face of daily uncertainty.
A more rigorous study is being designed to answer these research questions more definitively.
Thus, most data are of low quality, which partly results from the nature of the study question, which is difficult to answer by means of rigorous research methods.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com