Sentence examples for rigorous lineage from inspiring English sources

Recent use of more rigorous lineage tracing tools have strongly called into question the ability of epithelial cells to transition into collagen-producing mesenchymal cells during repair processes in numerous tissues, such as the kidneys [ 63- 65], liver [ 66- 68] and lungs [ 69].

Despite a wealth of literature supporting both theories, a growing number of recent studies employing much more rigorous lineage tracing analysis have cast a significant degree of doubt on the notion that fibrogenic cells arise from sources outside of tissue-resident MSCs.

We showed that the estimation of rigorous lineage-specific mutation rates for each locus allows the inference of robust split times in a species tree framework.

This is not terribly surprising for the cell types/numbers in an animal that follows a very rigorous cell lineage for generating neurons; connectivity is obviously another story but it is accepted that most invertebrates have a highly hard wired nervous system that varies very little with activity or the environment, or even with genetic variations.

The ability to classify other developmental lineages in this rigorous manner would be a significant advance for developmental biology and for regenerative medicine, which greatly depends upon understanding and selecting pure populations of precise cellular types.

Such data precluded any possible rigorous comparison between the two lineages of parasites because of a lack of overlap between stages analyzed in the hominid and rodent lineages.

If some lineages experienced more relaxed or rigorous selection than others in the light of divergence distances, the dN value should reveal a poor linear fit than dS value.

Thus, we need more extensive sampling of whole chloroplast genomes from the major lineages of flowering plants and more rigorous phylogenetic analyses before the full potential of this approach can be realized.

Despite the apparent consistency between our results and the report of adaptive specialization along the S. cerevisiae lineage, we found it difficult to establish a rigorous relationship between the quantitative function of the network and the network's fitness landscape.

Rigorous quantification of the gene regulatory circuits that govern cell lineage choice and subsequent mapping of the epigenetic landscape can potentially help identify optimal routes of cell fate reprogramming.

To identify genes that are likely to be important in the high altitude adaptation of P. erythrurus, we used rigorous criteria to identify candidate positively selected genes (PSGs) in the lineage.