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Using the US FDA pathway for rigorous development of disease-specific PRO tools, we have developed and validated a new patient-reported sign and symptoms measure for clinical trials and clinical use in UC.
Using the US FDA pathway for rigorous development of disease-specific PRO tools, we have developed and validated a new patient-reported sign and symptoms measure for clinical trials and clinical use in CD.
It is explained that the object of the book is to develop intuitive mathematical understanding rather than to give rigorous development of the topics considered.
Developing a mental health care plan in these settings requires rigorous development of interventions and a broad-based support from the community and policy makers.
They provide a rigorous development of the mathematical tools and apply them to understand the pricing models developed for use in the financial markets.
Euclid realized that a rigorous development of geometry must start with the foundations.
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Thus, this study covers critical issues that have not been systematically addressed in temporal RNA-seq data and we hope this will motivate more rigorous developments of novel methods to model and analyze RNA-seq data.
Finally, we outline the path to a more rigorous development in terms of standardization, accreditation, and procurement policy.
Traditionally, this process has benefited from the rigorous development and testing of hypotheses using tools derived from classical psychophysics and computational motor control.
Our objective is to improve self-efficacy, quality of life, self-care, blood pressure, cholesterol and glycemic control and promote exercise in people with type 2 diabetes through the rigorous development and use of a web-based patient self-management intervention.
Conceptually these two items, which require specific objectives and a well-defined clinical question, fit well with a process of rigorous development.
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