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Thus, oxygen exchange at 1- O-ribose during the macrodomain catalyzed reaction is not a rigorous consequence of the proposed 1- O-hydrolysis mechanism.
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Consumers must be fully informed of the potential consequences of assisted reproductive technologies, and the F.D.A. should commission rigorous outcome studies and consider stronger regulations rather than allowing the marketplace to drive the use of these technologies.
In consequence, rigorous confidence intervals reflecting these sources of uncertainty in the prediction can be obtained and used to assess the performance for the wind speed and wind turbine power forecasting.
The commission's chairman, Graeme Samuel, added: "At the heart of the ACCC's decisions are concerns about innovation, and as a consequence future rigorous and effective competition between retail investment platforms".
"Following a CQC inspection in early 2011, and as a consequence of rigorous clinical governance within the trust, significant changes have been made to ensure patient care is excellent which is resulting in the trust currently producing a SHMI below the national average.
A feared consequence of rigorous glycemic control is an increased incidence of hypoglycemia (49, 50).
The market does not provide all solutions and it is sloppy to allow it to become the arbiter of a nation's future and negligent to denationalise and deregulate without rigorous analysis of probable consequences.
His principal concern was to clarify general relativity's mathematical structure and its consequences, separating rigorous proofs from heuristic conjectures.
Clinical trials rarely collect sufficient data on treatment costs and consequences for rigorous economic assessment.
One of the most feared consequences of rigorous glycemic control is an increased incidence of hypoglycemia (1, 2).
However, such intervening events as having affected relatives and seeking regular medical care are not necessarily limitations to the study, as they are likely common aspects of being a member of a high-risk melanoma-prone family and, in the case of more rigorous professional screening, a desired consequence of genetic counseling and test reporting (26).
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