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We therefore envision trCYK's future role as a rigorous baseline against which more heuristic local RNA structural alignment methods may be compared.
Recently, many groups have incorporated both more rigorous baseline CNS staging (with mandatory CSF flow cytometric analysis) and earlier CNS-directed therapies (both systemic and IT) into future treatment protocols (Holte et al, 2013).
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Historical exploitation of the Mediterranean Sea and the absence of rigorous baselines makes it difficult to evaluate the current health of the marine ecosystems and the efficacy of conservation actions at the ecosystem level.
Effective conservation requires rigorous baselines of pristine conditions to assess the impacts of human activities and to evaluate the efficacy of management.
In the absence of longer-term data from which to establish more rigorous baselines, we defined a threshold for WS outbreaks across all locations by statistically isolating unusually high disease events.
It is only with this kind of rigorous entomological baseline that we can hope to project future health impacts of these viruses.
Importantly, the positive associations were present despite rigorous adjustment for baseline characteristics including brachial 24 h-MAP.
First, to reduce the impact of treatment selection bias and potential confounding in an observational study, we also performed rigorous adjustment for baseline differences by use of propensity score matching.
However, our study is the first to examine the effects of IIT on outcome in this population, applying rigorous adjustments for patients' baseline characteristics.
First, the clinician should perform a neurosensory evaluation to ascertain whether the patient indeed experiences altered sensation signs, and document the findings (Rosen, 2014; Givol et al., 2011; Pogrel, 2007; Juodzbalys et al., 2011; Givol et al., 2010), as a baseline for a rigorous follow-up (Rosen, 2014; Pogrel et al., 2011).
Analysis of the data obtained involves a rigorous methodology for setting the data baseline in compliance with solid mass balances.
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