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We performed rigorous adjustments for differences in the baseline characteristics of patients using the propensity score.
However, our study is the first to examine the effects of IIT on outcome in this population, applying rigorous adjustments for patients' baseline characteristics.
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A rigorous adjustment process was employed in preparing pattern swing values for future swing estimation.
Importantly, the positive associations were present despite rigorous adjustment for baseline characteristics including brachial 24 h-MAP.
Rigorous adjustment for potential differences in baseline patient characteristics was performed by propensity-score matching of covariates.
Another explanation for the significant effect on physical activity in our study might be the higher number of included patients or a more rigorous adjustment for wearing time.
In additional file 1, we derive a more rigorous adjustment but then we show that it does not result in further modification of the number of LC deaths.
Perhaps due to a more rigorous adjustment process, the estimates reported here are similar, but generally lower than those reported earlier [ 9].
First, to reduce the impact of treatment selection bias and potential confounding in an observational study, we also performed rigorous adjustment for baseline differences by use of propensity score matching.
Following rigorous adjustment (24 h mean arterial pressure and conventional risk factors), 24 h-CASP and 24 h-CPP increased with diabetes, albuminuria degree, previous cardiovascular disease (CVD), retinopathy and autonomic dysfunction (p ≤ 0.031).
Similarly, we were not able to obtain more detailed baseline data on all patients, including comorbidities and other risk factors, which would have allowed a more rigorous adjustment in the statistical models.
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CEO of Professional Science Editing for Scientists @ prosciediting.com