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In fact, insertion of either long helical linker or a rigid large protein domain did not deteriorate PPI detection, while FRET signal was barely detectable when Fn7-8 was inserted.
Since atherosclerotic mice are expected to develop high blood pressure and have rigid large arteries, simulations below studied changes in blood pressure at input of the VAN to simulate measures of blood flow change during a single ECG cycle.
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The values of the model parameters were identified and studied statistically based on 4 types of rigid large-span roof models in which 115 typical wind tunnel pressures were measured.
After adding COL.I/II, the layers became relatively more rigid and large aggregates were evident.
For a proof of principle of our LO-refinement procedure, we generated two types of datasets using the structures of ribosomes with two relative rigid modules (large and small subunits).
Fitting to a domain which should be as rigid and large as possible is one of the options.
Although the results suggest that the PIP2 binding site is likely not rigid, a large fraction of docked poses exhibits important commonalities.
4, 24– 29 However, such procedures are subjective because while each domain may move as a rigid unit, large conformational changes often involve tightly coupled motions between domains of the biological system.
4, 27– 29 Such procedures are subjective because while each domain may move as a rigid unit, large conformational changes often involve tightly coupled motions between domains of the biological system.
31– 34 Covered stents usually resist tumor ingrowth and therefore prevent re-obstruction but are less stable and more rigid, requiring larger delivery systems and are more prone to migration.
This paper addresses the problem of generating unstructured meshes with fixed connectivity for large rigid body motion.
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