Sentence examples for rigid compound from inspiring English sources

A crystal structure of one rigid compound bound to BRAF confirmed its binding mode.

Interestingly, 4α-acyloxy-2α-bromopicropodophyllotoxins were easily converted to a more rigid compound 14 by an intramolecular Friedel Crafts alkylation reaction in the presence of BF3·Et2O when the reaction time was prolonged to 4 18 h.

The higher loading and large microsize of MS particles result in more rigid compounds.

However, cytotoxic effects of the compounds were not related to topo I inhibition which is explained by non-planar conformation of the rigid compounds incapable of intercalating between DNA base pairs.

We have designed a series of simple rigid compounds (2) having a phenyl ring attached to three essential groups necessary for selectin binding, i.e., a fucose unit, a carboxylic acid, and the hydrophobic part.

Since a distinct disfavor towards rigid compounds was observed for 5-HT7 receptonlyonly, it seems that the bioactive conformation of chain derivatives at those sites should differ from the extended one.

The second are class with more rigid compounds containing phenoxy or other cyclic groups on both ends of the molecule exemplified by ZR-10183, ZR-10131 and pyriproxyfen (Class II structures 81, 85, 86).

Remarkably, the DrugBank contains the largest fraction of very rigid compounds bearing no or only 1 and 2 rotatable bonds.

More flexible compounds 10 12 display affinities for Kef similar to those of the more rigid compounds (e.g., compounds 6 and 12) in both the fluorescence and DSF assays.

A new type of rigid PVC compound with higher toughness and higher heat resistance was prepared by using a new type of PVC modifier, ultrafine full-vulcanized powdered rubber (UFPR).

Considering that the mean MW of TCMCD1 is significantly larger than that of ACD1, natural compounds in TCMCD1 are substantially more rigid than compounds in ACD1.