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In a study published earlier this year, healthy, active men were assigned to run for an hour on one day and on another, to ride vigorously for the same amount of time.
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Interestingly, the muscle cell methylation changes were far more pronounced among the volunteers who had ridden vigorously than in those who had pedaled more gently, even though their total energy output was the same.
There would seem to be little new to do with "Private Lives," for example, which long ago became a campy war horse to be ridden vigorously by stars of a certain age (Tallulah Bankhead, Elizabeth Taylor, Joan Collins, etc).
The volunteers rode vigorously on a stationary bike, flexed their ankle while lying in a machine that measured an index of tiredness in the muscle, and had muscle biopsies taken.
The men were not all athletes, but they did have to be able to ride a bike vigorously.
To find out, the researchers had the volunteers either vigorously ride computerized stationary bicycles or sit quietly for an hour before settling onto the M.R.I. tables.
He shook my hand vigorously and rode off with the suggestion that I think about what he had said.
It spins its tires vigorously at the least excuse, and when unloaded, the ride is somewhat jouncy and bouncy.
Despite all the guests diving, shrieking out of windows in fear of their lives, Mytton was furious that his entrance had not been more dramatic so rode out and re-entered, this time applying the spurs vigorously.
As a candidate, Mr Obama applauded the courage of whistle-blowers (and rode into the White House on their disclosures); as president he has prosecuted them far more vigorously than his predecessors did.
Screw vigorously.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com