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Refinement was conducted using phenix.refine, interspersed with manual revisions of the model using Coot.
As time passed and more relevant empirical data became available, updated revisions of the model were released.
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The bank said that some other assumptions built into the models failed to anticipate the "continued unprecedented uncertainty and turbulence" in the market for servicing mortgages, resulting in a revision of the model and a $760 million charge.
It suggested a revision of the model for current educational methodology and integration of recent multinational analyses to provide comparability among institutes across the globe.
Accordingly, we expect that it will soon be possible to provide additional evidence that could lead to one of a range of outcomes, including support for the model, revision of the model, or rejection of the model.
The results were interrogated so as to identify and quantify agreement and disagreement with the constitutive model proposed previously (Adams AM, Buckley CP. Polymer 2000; 42: 771–786), thereby informing revision of the model.
A deeper consideration of the complexities, further testing and revision of the model, and serious reflection are all warranted.
For example, melanomas that fit into one of these subtypes, but which do not respond as predicted, may necessitate splitting of that subtype in a future revision of the model.
This points towards a potential revision of the model to account for this oscillatory behaviour.
Together, our findings lead to revision of the model for the morphogenetic events that drive peri-implantation development, the component steps of which we discuss below.
Together, our findings have uncovered a previously hidden sequence of morphogenic events and lead us to propose a complete revision of the model for the blastocyst to egg cylinder transition.
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