C.R.: data review and revision, manuscript preparation.
All authors participated in revision and preparation of the final manuscript.
SG wrote the first draft and all authors contributed to revision and preparation of the final draft.
She is the corresponding author and contributed to the writing, critical revision together with draft preparation, final preparation for manuscript submission, preparation and submission of all revisions.
Contributions to study conception and design, data acquisition, analysis and interpretation, draft preparation, revision and approval: KSG, PS, JMC.
RS: Supervision of antibody purification and detection assay; study conception and design; data interpretation; manuscript preparation, revision and approval.
All four authors participated in strategic planning, concept development, revisions, and manuscript preparation.
Both authors participated in the development of methodology, simulations, real data application, revisions, and manuscript preparation.
We would like to thank Christine Nelson for her invaluable assistance with revisions and final preparation of the manuscript.
R.B.: data collection, manuscript preparation and revision, D.G.: study design, data collection, data analysis and manuscript revision.
