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See Essential Revision Point #2.
Please see Essential Revision Point #2.
Please see Essential Revision Point #1 above.
We have tested this in an experiment (please see Essential Revision Point 3).
Please see Essential Revision Point #3, where these points have been addressed.
2) Regarding Essential Revision point #6, the authors appear to have misunderstood the concern.
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Please refer to our response to "Essential Revisions" point #2 above.
As mentioned in response to "Essential Revisions" point #1, we have conducted the control experiment involving AC5 knockout tissues and report it in revised Figure 1. 2) Figure 2 reports a BRET assay designed to detect Golf activation based on free beta-gamma binding to a NanoLuc-labeled GRK2. 10 μM dopamine caused a BRET change that was reversed by 100 μM haloperidol.
And just as a debating society could not function if its ground rules were constantly open to debate and revision at point of application, a constitution could not serve its role if its terms were constantly open to debate and revision by participants within the political and legal processes it aspires to govern.
Only follow-ups within ±5.5 years around the revision time point were analyzed.
Follow-ups within ±5.5 years around the revision time point were analyzed.
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CEO of Professional Science Editing for Scientists @ prosciediting.com