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The authors should consider revising this point and elaborate the Discussion.
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Either their economic optimism would prove correct, in which case the stimulus would have to be rapidly withdrawn, or the caution of the central banks would turn out to be justified and profit forecasts would have to be revised lower.On this point, the evidence is mixed.
Considering the anticipated difficulty of the surgery and the medical condition of the patient, only the right hip was revised at this point.
Please follow my original comments and revise point-by-point your manuscript.
The revised manuscript clarifies this point in the Results and Discussion sections.
Since the metabolic labeling of DGFc340 with [3H]-Xylose was not successful we did not include this data in the revised manuscript at this point.
In order to pre-empt such misunderstanding we have, in the revised manuscript, explained this point in greater detail in the Introduction of our manuscript.
The text in the second to last paragraph of the subsection "In vitro BiP oligomerization by cross-protomer engagement of the interdomain linker at trans substrate binding sites" has been revised to incorporate this point.
The text was revised to explain this point, making use of the concepts of active and quiet wakefulness, and better explain the data presented in Figure 3. 2) At present no detailed molecular details or neuronal control circuits can be deduced from the work notwithstanding that the authors show an influence of PKA signaling on the behavioral changes surrounding/during lethargus.
As regards the question of whether the activity remaining in the EMCV delta L virus is MDA5 dependent, we now state in the revised Discussion that this point is unclear and have added a new figure to support that statement (new Figure 5 figure supplement 1).
The title of Figure 4 and the related contents in the text have been revised to clarify this point that it is not a contamination per se but a factor that needs to be considered when analysing, reporting results and investigating miRNA protein targets.
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CEO of Professional Science Editing for Scientists @ prosciediting.com