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KH was the principal investigator and revised the trial protocol and the manuscript.
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These were more favourable than initially planned (SD=21, r=0.60), and we revised the total trial sample size downwards to 60 participants per arm to maintain 80% power to detect a difference of 10 units with these revised parameters.
T.S./S.P.C. helped with trial design, managed the trial and revised the paper.
EFE: designed the clinical trial, procured funding for the study, directed the implementation of the trial, and revised the draft.
After the termination of the trial, we revised the original interview guide (provided in Additional file 1) to explore actual and potential participants' reasons for deciding to participate or not in the trial and their views about whether, how and why HSE has been helpful in their work, what features are most and least helpful and why, and recommendations for how to improve it.
MK is involved in the supervision of the trial and revised the manuscript.
JW is involved in the supervision of the trial and revised the manuscript.
MWB is involved in the supervision of the trial and revised the manuscript.
LLY participated in the design, selected the trials and revised the manuscript critically.
BF, PJ, HL, JLH, CG, BO, and BG participated in the design of the trial and critically revised the manuscript.
KvW participated in the design of the study, had the lead of the cohort during the trial period and revised the manuscript critically.
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