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Potential participants were identified by reviewing database of public health institutions and FMS registry maintained by the Ministry of Health, Malaysia and the Malaysian Family Physician Association, respectively.
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Staff at each EIP site identified cases by contacting hospital laboratories, medical records departments, and infection control practitioners, and by reviewing databases of state-reportable conditions.
Methods: We retrospectively reviewed database of 51 post-arrest patients treated with TH in our hospital from 2006 to 2014.
We used metabolite formulas in Recon 2 to review database identifiers that were added to the reconstruction (see Additional file 1: Section 2).
We used UniProtKB/Swiss-Prot database (Magrane and UniProt Consortium, 2011), which is a manually curated and reviewed database.
In order to do so, we extracted the set of peptides from UniProtKB/Swiss-Prot database [ 31], release 2013-01, whish is a manually curated and reviewed database.
Annotations within these high-confidence subsets were required to exactly match sequences in Uniprot's [ 3] reviewed database and to be listed and as possessing protein level evidence.
LC-MS data were processed and searched using Waters ProteinLynx Global SERVER version 3.0 (PLGS, Waters) and identified, using the UniProt Human reviewed database (UniProtKB release 2014_11, 20265 entries).
We carried a broad search of manually reviewed databases, which yielded seven studies that met out inclusion criteria.
In order to detect putative toxins, reviewed databases from Uniprot annotation program Tox-Prot [ 68] and home-made mature peptide sequences database were used.
In the second paper, Gromiha & Ou review databases, online resources and sequence analysis techniques to characterize membrane proteins primarily from their amino acid sequence.
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