M D Post reviewed histopathology, performed immunoreactivity scoring and provided intellectual expertise.
In FOCUS, the percentage of ranibizumab-treated patients testing positive for immunoreactivity did not exceed the percentage in the PDT-alone group, and review of the VA data and AEs revealed no clinically relevant effects in patients with positive immunoreactivity (Heier et al. 2006b).
CEACAM immunoreactivity of tumour cells was compared with that in normal lung epithelial cells that were negative for immunoreactivity.
The staining intensity was graded on a scale of 0 to 3+ (0 for no staining, 1+ for weak immunoreactivity; 2+ for moderate immunoreactivity; and 3+ for strong immunoreactivity).
Review for spelling errors.
Check reviews for products online.
For histological evaluation of TM immunoreactivity, the staining was scored independently by two observers blinded to the clinical outcome; discordant scores were reviewed, and a consensus was reached.
In VHL+/− animals, there were random epithelial cells that were negative for VHL immunoreactivity; and in EAF2−/−VHL+/− prostates, some areas of PIN were negative for VHL immunoreactivity.
Hippocampal tissue from representative animals was later analyzed by Western blot for CREB immunoreactivity.
The two patients tested for cellular immunoreactivity to vaccinia antigens showed strong responses.
