Exact(1)
Further evidence implicated increased capacity to resist oxidative damage in mice survival [ 43], particularly thanks to studies on p66(Shc), a crucial regulator of ROS levels whose deletion in mice prolongs lifespan (See Trinei et al. [ 44] for recent review) Efficient renewal of functional mitochondria is known to reduce mitochondrial ROS production [ 7].
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Justyna Jupowicz-Kozak
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