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Nonepigenetic gene regulation is short-term, and expression reverts upon withdrawal of the relevant factors.
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The endothelial dysfunction and platelet aggregation responses mediated by reelin were reverted upon treatment of a reelin neutralizing antibody.
Circular dichroism (CD) spectra reveal that DNA undergoes important conformational changes upon adsorption onto the core-shell surface, which are reverted upon TMPyP encapsulation.
For Proclus, souls as self-moving principles represent the lowest level of entities that are capable of reverting upon itself (so called self-constituted beings [authypostata], see Elem. Theol. § 40 51).
However, this differentiation block was reverted upon doxycycline treatment of CombitTA-FUS-DDIT3 MEFs (15 25%) (Figure 2B).
In summary, mPIN lesions in young MPAKT mice were fully reverted upon RAD001-treatment; however, mPIN lesions in Hi-MYC and MPAKT/Hi-MYC bigenic mice did not respond to RAD001 despite effective mTORC1 inhibition.
Transformation could be temporarily delayed and even partially reverted upon feeding fresh medium, but eventually continued to progress until all structures were thoroughly transformed and only stellate structures remained (Figure 2g).
Interestingly, functional anergy of both CMV and LCMV specific, PD-1 positive T cells was shown to be reverted upon blockade of PD-1 with its ligands [20], [27].
Based on the observation that CTL escape mutations revert upon transmission [27], [32], [35] Leslie et al. were the first to conclude that this may be driven by a gain of fitness, implying that at least some CTL escape mutations come at a substantial fitness cost [27].
These changes were reverted upon CSC differentiation.
Most expression changes in senescence were reverted upon hTERT expression (Fig. 1E).
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