Recent studies show that patients with mild cognitive impairment have a high risk of progressing to dementia, even if they had reverted to normal cognitive functioning [ 52].
Ryde pier, wistfully remembered from childhood by the author and former Tory MP Gyles Brandreth as "the first in my life", has reverted to its original function as the drab landing stage for Isle of Wight ferries, but at its height it had a 700-seat domed pavilion, reading and refreshment rooms, and a sun lounge.
55 Furthermore, when compared to insulin glargine, exenatide treatment for 52 weeks significantly improved β-cell function as assessed by arginine-stimulated hyperglycemic clamp, and the β-cell function reverted to pre-treatment levels after discontinuation of exenatide therapy.
In the 1920s and much of the 1930s, the General Staff tried to establish a small, mechanised, professional army and formed the Experimental Mechanized Force, but with the lack of any identified threat, its main function reverted to garrison duties around the British Empire.
After 1 month of washout, β-cell function reverted to pretreatment values (34).
However, in the triple-mutant background ben1-1 was reverted to a partial loss-of-function allele showing enhanced levels of the wild-type-spliced transcript.
This low reversion rate is consistent with the very specific nature of the reversion assay in which each strain is able to revert to Trp+ function via only one specific base pair change (Williams et al. 2005).
Research on dynamical diseases in complex adaptive systems has shown that pulsed, properly-timed stimuli can interrupt the dynamics of a pathophysiological process such as a seizure [ 226] or a cardiac arrhythmia [ 227] and cause the affected system to revert to normal function [ 228].
I knew the mutations were central to antibody function because they lost their binding and neutralizing activity when reverted to their germline sequences (3, 7).
For example, a borderline thyroid function test may be repeated after 3 6 months to determine whether it has become abnormal or reverted to normal.
