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The key to the mystery is how the cells of the jellyfish "know" when to revert to stem cells and when to differentiate again.
These precursors are normally destined to differentiate into Paneth and enteroendocrine cells, but have the capacity to revert to a CBC stem cell upon tissue damage.
However, when EpiSCs were reverted to ESC-like cells and subsequently induced into a pre-gastrulating mouse EpiLC state, they gained the ability to differentiate into Blimp1+/Stella+ PGCLCs in response to BMP4 (Hayashi et al, 2011).
You have to differentiate".
People want to differentiate themselves".
There is a need to differentiate.
I've always been able to differentiate.
I wanted to differentiate myself from Portlandia.
It's another way to differentiate themselves".
He wanted to differentiate it from xenophobia.
Then we started to differentiate our products.
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