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Established mechanisms of resistance to imatinib are discussed, as are novel therapeutic approaches to improving drug responsiveness by reversing development of imatinib resistance in patients.
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In a resolution of the 65th General Assembly of the UN, it is clearly stated that "the financial and economic crisis... has reversed development gains in many developing countries and threatens to seriously undermine the achievement of the Millennium Development Goals".
These factors could reverse development gains, it says.
"Reverse development" may be as important for the next 60 years, as north-south development has been for the past 60.
"Reverse development" is what we need, and we should set up a northern based agency staffed by southerners to help build our own capacity to meet the SDGs.
DfID has previously been warned that its strategy in fragile states will take time to bear fruit, as renewed fighting and corruption can reverse development gains.
Conclusion: Prenatal repair of myelomeningocele prevents or reverses development of hindbrain herniation in the fetal lamb model.
In act there is mounting evidence that these ever more frequent shocks threaten to reverse development progress in low-income countries.
Climate change over the course of the century could create environments so hostile it would reverse development and force the movement of hundreds of millions and possibly billions of people.
Congo's stagnation or even worse, its reverse development — this year the United Nations ranked it dead last of the 187 countries on the Human Development Index — is driving many people to vote against Mr. Kabila, who has been in power since 2001.
"The negative consequences of climate change are already disrupting these countries' development trajectories, with potential to reverse development trends by mid-century," the expert said.
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