Your English writing platform
Discover LudwigExact(1)
A 3D-QSAR study using CoMFA and CoMSIA was carried out to decipher the factors governing MDR reversing ability in cancer.
Similar(59)
Hepatic vagotomy only partially reversed the ability of central leptin to improve glucose tolerance.
Pre-treatment with the PP2A inhibitor okadaic acid (OA) did not reverse the ability of propofol to inhibit LPS-induced upregulation of nitrite in macrophages (20.6±1.9 without OA vs. 20.1±1.1 with OA, Figure 4A).
In reporter assays, we found that expression of the PIAS1 (CS) mutant, but not the wild type PIAS1, reversed the ability of SnoN to counter TGFβ-repression of E-cadherin transcription (Figure 7D).
Additionally, siRNA specifically targeting topoisomerase IIα did not reverse the ability of TPZ to inhibit HIF-1α expression, suggesting that the HIF-1α inhibitory activity of TPZ is independent of its topoisomerase IIα inhibition.
The use of the transwell barrier reversed the ability of WSX1 to reduce T cell number and IFNγ production in T cells (Figure 6a, 6b), suggesting that WSX1-positive tumors initiate immunosuppression via a direct tumor/immune cell contact-dependent manner.
Conversely, the 3F mutation reversed the ability of p66Shc to inhibit B-cell chemotaxis, as well as adhesion and polarization.
Upon LPS stimulation, GW9622 (10 μM) did not reverse the ability of rosiglitazone to block NO release and PGE2 production.
Moreover, inhibition of MEK/ERK with U0126 also reversed the ability of Six1 to induce transcriptional activation of the β-catenin TOP-FLASH reporter.
Deletion of TSG6 in human MSCs reverses their ability to repair myocardial infarct, corneal damage and fails to prolong the corneal allograft survival.
Similar results were obtained in the CAM assay, as the IκBα mutant reversed the ability of CM collected from URG4/URGCP-overexpressing HCC cells to promote angiogenesis.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com