Sentence examples for reversed t from inspiring English sources

It is important to note, however, that previous studies from our group showed that therapy with anti-PD-1 and anti-PD-L1 antibodies reversed T cell dysfunction and improved survival in both primary candidiasis and in a two-hit model of fungal infection [ 11].

Two different MFC configurations designed for handling solid wastes as a feedstock were evaluated in batch mode: a single compartment combined membrane-electrodes (SCME) design; and a twin-compartment brush-type anode electrodes (TBE) design (reversed T-shape MFC with two-air cathode) without a proton exchange membrane (PEM).

Darpp-32 co-expression reversed t-Darpp's effects on Herceptin resistance and Akt phosphorylation.

In animal models, blockade of PD-1 partially reversed T-cell exhaustion, and multiple blockades of inhibitory receptors enhanced T-cell function more efficiently.

Our data suggest that sPD-1 may be a promising biomarker for diagnosing and determining the prognosis of RA. sPD-1 and inflammatory mediators of patients with RA significantly attenuated or reversed T-cell suppression mediated by PD-L1-Fc, verifying that sPD-1 acts as a natural blocker of PD-1/PD-L1 signandng and that soluble factors may interfere with this negative pathway.

A modified cross viscosity model has been formulated to identify the filling capability of straight, reverse 'T' and cross '+' shape micro channel with various sizes.

Thus we believe that elucidating the underlying mechanisms of CAR-T cell therapy resistance and development of effective combination therapy that combination of PD-1/PD-L1 blockade with CAR T cell therapy in an effort to reverse T cell exhaustion will be an active research area in CAR-T cell therapy field.

In contrast, it can be envisioned that the transfer of active Ras a G-protein known to reverse T cell anergy [29] and promote the acquisition of proinflammatory effector functions from tumor cells to lymphocytes may serve as a 'stimulatory' signal for the immune system to eliminate nascent tumors expressing oncogenic forms of Ras.

Therapy that reverses T cell exhaustion may restore immune function in immunocompromised patients and improve survival in sepsis.

If the loss of T cell function is antigen-driven it can be proposed that the removal of the stimulating antigens might reverse T cell anergy.

Data were expressed as the arithmetic means ± standard deviation (S.D .. To assess the involvement of IL-10 in reversing T cell suppression, we sorted CD4+ CD25- and CD4+ CD25+ CD44+ (or CD4+CD25+ cells) cells via FACS.